SANTA CLARA, Calif., May 17, 2007 – The Affymetrix ChIP-on-chip Workflow provides guidance on chromatin immunoprecipitation (ChIP) coupled with microarray technology to ensure optimum results when using Affymetrix high-density tiling arrays.

ChIP-on-chip is a powerful new technique for enriching and identifying genomic DNA sequences bound by transcription factors and identifying sites of DNA and histone modification.  Key steps that are discussed in this workflow include:

• Cell fixation
• Sonication
• Immunoprecipitation
• Amplification
• Hybridization
• Quality control checkpoints

Download the ChIP-on-chip Workflow