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The Mouse Genome Sequencing Consortium (MGSC) version 3 assembly was used to design the Mouse 430 set. Specifically, the genomic sequence was used for trimming low quality portions of EST sequencing reads and for improving orientation calls through the use for flanking intronic sequence. The probe sets themselves are constructed against the consensus sequence for cDNA sequence clusters. The Mouse 430 set is not a genome tiling product, but rather an mRNA expression product; thus the entire mouse genomic sequence is not represented. |