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CustomSeq Resequencing Array

Frequently Asked Questions

  1. How many bases can I resequence on a CustomSeq array?

  2. Do I need to resequence one long region or may I also use this to sequence several shorter ones?

  3. How many probes/features per base?

  4. How many arrays do I need to order?

  5. What is the turn around time for a new CustomSeq array design?

  6. How long does an experiment take?

  7. What Affymetrix instrumentation, hardware and software is required to run the CustomSeq assay?

  8. What support materials are currently available on CustomSeq?

  9. What publications are currently available on CustomSeq?

  10. What is your overall accuracy? How does it compare to capillary sequencing?

  11. Do I need to manually check heterozygotes?

  12. What is your call rate? How does it compare to capillary sequencing?

  13. What is your reproducibility?

  14. What are the benefits of longer read-length?

  15. Can I detect Insertions or Deletions on a resequencing array?

  16. How much DNA is required?

  17. Can I analyze only one strand? Your chip holds 600 kb but you tile 300 kb double - stranded - can I just tile one strand and sequence a full 600 kb?

  18. Can the CustomSeq array detect heterozygotes?

  19. What does the quality score stand for?

  20. How does the quality score compare to Phred/ Phrap scores?

  21. How does CustomSeq handle GC rich regions?

  22. Can I use genotype for individual SNPs in many genes?

  23. What is the difference between GSEQ software and the ABACUS program offered through JHU?