The various vignettes below provide brief and concise information on specific topics.
More current information on these topics may be available through affymetrix.com.
- Masking Out Probes in apt-probeset-summarize: This document provides information on how to exclude probes from an expression analysis using apt-probeset-summarize. For example, one might use this approach to exclude probes which overlap known SNPs.
- SNP6 Copy Number Component Workflows: This document provides information on using the individual APT components to do a copynumber analysis on SNP 6.0. Most users should use apt-copynumber-workflow (which is not described here). Use of the individual components provides greater flexibility with regard to the low level aspects of the copynumber analysis.
- Copy Number Workflows for Genome Wide SNP6 using apt-probeset-summarize: This document describes an earlier workflow which uses apt-probeset-summarize to extract signal estimates (not to be confused with copynumber estimates) for copynumber and genotype probesets. This workflow probes a way to extract low level probeset summaries as a starting point to a copy number analysis. Most users should use apt-copynumber workflow rather than the workflows described here.
- SNP Array Analysis - genotype calling with just one sample: This document provides information on how to generate genotype calls without requiring multiple sample clustering. This application is geared toward quality assessment workflows where the absolute best genotype calls for the largest number of SNPs are not necessary.
Affymetrix Power Tools (APT) Release apt-1.10.0
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1.5.3