Learn more about the non-polymorphic probes on the Genome-Wide SNP Array 5.0

The SNP Array 5.0 contains 420,000 non-polymorphic probes for researchers to examine germline copy number variation (CNV) in association studies. One hundred thousand non-polymorphic probes cover 2,000 known CNVs identified in the UCSC Genome Browser database (50 probes per CNV). Another 320,000 probes were chosen to give even spacing across the genome, concentrating on areas not represented by SNPs. Current Affymetrix software does not support analysis of the non-polymorphic probes.

Figure 1: Coverage of SNPs and non-polymorphic probes on the Genome-Wide SNP Array 5.0