High density GeneChip® Tiling arrays are a discovery tool to study gene regulation. Tiling arrays complement expression analysis arrays and offer a tool to explore genome functions including:
Quickly derive biological significance from array data
Preview array content before research begins
Open access to comprehensive public domain and Affymetrix annotations through one interface
Software Development Tools for Regulation
Interested in developing software for the analysis of Regulation data? Visit the Affymetrix Developers' Network for a complete set of regulation resources.
High-resolution Tiling Arrays Used to Map Genome-wide Methylation Patterns in Arabidopsis The Salk Institute’s Joseph Ecker and Lawrence Livermore’s Jutta Kollet discuss the first study to map the methylome in Arabidopsis. Read AMB article
AMB Symposium: ChIP-on-chip: Defining the Estrogen Receptor Cistrome Dr. Brown discussed the ChIP-on-chip mapping of estrogen receptor binding sites in breast cancer cells, and how his lab’s recent work has challenged the classic paradigm of promoter-proximal binding. Read AMB article
AMB Symposium: Analysis of ChIP-on-chip data using Affymetrix Genome Tiling Microarrays Dr. Liu discusses the technology of ChIP-on-chip using genome tiling microarrays, model-based analysis of tiling arrays (MAT) for peak identification as well as other related algorithms such as array image quality control, probe mapping and downstream analysis of the peaks. Read AMB article