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GeneChip Compatible Software
 

High density GeneChip® Tiling arrays are a discovery tool to study gene regulation. Tiling arrays complement expression analysis arrays and offer a tool to explore genome functions including:

DNA Methylation
Origins of Replication
Mapping sites of transcription factor binding
GeneChip® Arrays for Gene Expression Regulation
    View archived webcasts on regulation:
  Fundamentals of the ChIP-on-chip assay
Methods behind analysis of ChIP-on-chip data
Integrating Regulation and Expression Data for Software Developers
Six-part ChIP-on-chip Symposia Series
     
NetAffx Analysis Center
Annotations, Sequences, and Tools
   
 
Quickly derive biological significance from array data
  Preview array content before research begins
  Open access to comprehensive public domain and Affymetrix annotations through one interface
Software Development Tools for Regulation
  Interested in developing software for the analysis of Regulation data? Visit the Affymetrix Developers' Network for a complete set of regulation resources.
Additional Support
  ChIP-on-chip Application Note (pdf, 487 KB)
   
     
Affymetrix Microarray Bulletin
  Featured Articles
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High-resolution Tiling Arrays Used to Map Genome-wide Methylation Patterns in Arabidopsis
The Salk Institute’s Joseph Ecker and Lawrence Livermore’s Jutta Kollet discuss the first study to map the methylome in Arabidopsis.
Read AMB article

AMB Symposium:  ChIP-on-chip: Defining the Estrogen Receptor Cistrome
Dr. Brown discussed the ChIP-on-chip mapping of estrogen receptor binding sites in breast cancer cells, and how his lab’s recent work has challenged the classic paradigm of promoter-proximal binding.
Read AMB article

AMB Symposium:  Analysis of ChIP-on-chip data using Affymetrix Genome Tiling Microarrays
Dr. Liu discusses the technology of ChIP-on-chip using genome tiling microarrays, model-based analysis of tiling arrays (MAT) for peak identification as well as other related algorithms such as array image quality control, probe mapping and downstream analysis of the peaks.
Read AMB article

 
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