GeneChip expression arrays enable researchers to simultaneously monitor genome-wide expression profiles. This global view helps scientists understand biological mechanisms of complex diseases and processes, and identify new drug targets in ways never before possible. Utilizing gene expression profiles as novel "biomarkers," for conditions such as cancer or lupus, scientists are able to more accurately classify disease, predict clinical progression, and determine likelihoods of treatment success.
Transcriptome Mapping
In addition to GeneChip arrays that quantitate known and annotated transcripts, new GeneChip® Tiling Arrays can be used as a discovery tool to identify novel transcriptional elements and evaluate antisense transcription. Tiling arrays are designed to interrogate genomes at regular intervals, including both annotated and so-called “junk” regions of a genome. Using this neutral approach to array design, tiling arrays have been used in transcriptome studies to discover new thousands of previously unknown transcripts.
