miRNA Array Strip
Affymetrix® miRNA Array Strip is a powerful tool for studying the role of small non-coding RNA (miRNA, snoRNA, and scaRNA) and their importance in cancer and other diseases.
Since their discovery in 1993, small non-coding RNAs (microRNA, scaRNA, and snoRNA) have emerged as a major component in the regulatory circuitry that underlies the development and physiology of complex organisms.
As a result, it has become increasingly important to complement messenger RNA (mRNA) gene expression studies with miRNA analysis in order to understand the biological context of differentially expressed genes. These key functional gene products are estimated to regulate approximately 30 percent of all protein-coding genes.
Keeping pace with the discovery of new and novel miRNA, Affymetrix is pleased to announce the release of the NEW Affymetrix® miRNA 3.1 Array Strip—the latest addition to our growing catalog of miRNA products.
Unique array content of Affymetrix® miRNA 3.1 Array Strip
miRNA arrays from Affymetrix provide the most sensitive, accurate, and complete measurement of small non-coding RNA transcripts involved in gene regulation. These are the only arrays with:
- 100 percent miRBase coverage, all organisms
- snoRNAs and scaRNAs
- Probe sets unique to pre-miRNA hairpins
| Performance specifications | miRNA 3.1 Array Strip |
|---|---|
| Reproducibility (inter– and intra-lot)* | ≥0.95 |
| Transcripts detected at 1.3 amol in 130 ng | ≥80% |
| Dynamic range | >3 logs |
| Total RNA input | 130–1,000 ng |
| *Pearson product moment coefficient correlation for comparison of signal within and between lots. | |
| Array contents | miRNA 3.1 Array Strip |
|---|---|
| miRBase version | 17 |
| Organisms | 153 |
| Total probe sets | 19,724 |
| Probes/probe set for mature miRNA | 9 |
| Human mature miRNA | 1,733 |
| Mouse mature miRNA | 1,111 |
| Rat mature miRNA | 680 |
| Human snoRNA and scaRNA | 2,216 |
| Human pre-miRNA | 1,658 |
| Mouse pre-miRNA | 855 |
| Rat pre-miRNA | 486 |
"For Research Use Only. Not for use in diagnostic procedures."
