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GeneChip® CHO Gene ST Arrays

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The whole-transcript coverage of this array provides the most accurate, sensitive, and comprehensive measurement of protein coding and non-coding RNA transcripts.

Part # Description Unit Size
GeneChip® CHO Gene 2.0 ST Array
Contains 6 arrays   
GeneChip® CHO Gene 2.0 ST Array
Contains 30 arrays   

Comprehensive design

The Chinese hamster ovary (CHO) cell lines were introduced in the 1960's and has become an extremely important tool for biomedical research biopharmaceutical manufacturing. Their rapid growth, stable gene expression profiles, and high protein production make them idea for both research studies and for the production of therapeutic proteins.

To help further your research and improve manufacture yield, Affymetrix has introduced GeneChip® CHO Gene 2.0 ST Array, with an expression array design that provides the highest coverage of the transcribed genome. We use a comprehensive collection of information sources to design probes that interrogate up to 23 unique sequences of each transcript. This design strategy provides you with the ability to evaluate whole-transcriptome gene expression at the gene and exon levels, which allows the study of transcript variants and alternative splicing events.

This unique array design is based on the most recent genome content and offers the high probe coverage of every transcript measured by this array. The high transcript coverage of this array design yields accurate detection for genome-wide transcript expression changes and provides higher resolution and accuracy than other classical 3'-biased microarray solutions on the market. The whole-transcriptome analysis approach enables researchers to detect multiple transcript isoforms from a given gene, including those that could be missed using a 3'-biased expression design, such as splice variants, non-polyadenylated transcripts, transcripts with alternative polyadenylation sites, and truncated transcripts.

Key benefits

  • Whole-transcript analysis the capture of transcript isoforms you may miss with 3'-biased expression designs
  • Comprehensive transcriptome coverage provides the best opportunity to discover interesting biology:
    • >21,000 protein coding transcripts
    • >19,000 Entrez genes
  • Measure alternative splicing events/transcript variants with probes designed to maximize coverage of exons
  • Reproducible: Signal correlation coefficient ≥0.99

Content profile

The tables below summarize the array content and data sources used to design GeneChip CHO Gene 2.0 ST Array.

Transcript coverage of the array1 CHO Gene 2.0 ST Array
Total RefSeq transcripts covered 21,542
NM – RefSeq coding transcript, well-established annotation 300
NR – RefSeq non-coding transcript, well-established annotation 5
XM – RefSeq coding transcript, provisional annotation 20,838
XR – RefSeq non-coding transcript, provisional annotation 399
RefSeq (Entrez) gene count 19,670

Data sources used to design the array CHO Gene 2.0 ST Array
RefSeq 51
Ensembl 65

"For Research Use Only. Not for use in diagnostic procedures."


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