Affymetrix Patents: Assays and Analysis As of August 2007

Affymetrix patents and published patent applications may be viewed at the United States Patent and Trademark Office web site and the European Patent Office web site. On this page: General Analysis Genotyping Expression and Profiling Electrochemical Analysis GENERAL ANALYSIS USPN Title Inventor 5324633 Method and Apparatus for Measuring Binding Affinity Fodor 5527681 Immobilized molecular synthesis of systematically substituted compounds Holmes 5541061 Methods for Screening Factorial Chemical Libraries Fodor 5710000 Capturing sequences adjacent to Type-IIs restriction sites for genomic library mapping Sapolsky 5834252 End-complementary polymerase reaction Stemmer 5871928 Methods for nucleic acid analysis Fodor 5902723 Analysis of surface immobilized polymers utilizing microfluorescence detection Dower 5928905 End-complementary polymerase reaction Stemmer 6037124 Carboxylated polyvinylidene fluoride solid supports for the immobilization of biomolecules and methods of use thereof Matson 6045996 Hybridization assays on oligonucleotide arrays Cronin 6090553 Use of Uracil-DNA Glycosylase in Genetic Analysis Matson 6124102 Methods for determining receptor-ligand binding using probe arrays Fodor 6203983 Method for Detecting Chemical Interaction Between Naturally Occurring Bipolymers which are Non-Identical Binding Partners Quate 6203989 Methods and Compositions for Amplifying Detectable Signals in Specific Binding Assays Goldberg 6228575 Chip-Based Specification and Phenotypic Characterization of Microorganisms Gingeras 6258536 Expression Monitoring of Downstream Genes in BRCAI Pathway Oliner et al. 6291181 Capturing Sequences Adjacent To Type IIs Restriction Sites for Genomic Library Mapping Gingeras et al. 6300070 Solid Phase Methods for Amplifying Multiple Nucleic Acids Boles et al. 6303301 Expression Monitoring for Gene Function Identification Mack 6306643 Methods of Using an Array of Pooled Probes in Genetic Analysis Gentalen 6309822 Method for Comparing Copy Number of Nucleic Acid Sequence Fodor 6309823 Arrays of Nucleic Acid Probes for Analyzing Biotransformation Genes and Methods of Using the Same Cronin 6329140 Identification of Molecular Sequence Signatures and Methods Involving the Same Lockhart 6333155 Exploiting Genomics in the Search for New Drugs Lockhart 6335161 Release of Intracellular Material Jene-Rene Martin 6340565 Determining Signal Transduction Pathways Oliner 6342355 Probe-Based Analysis of Heterozygous Mutations using Two-Color Labeling Hacia et al. 6355432 Products for Detecting Nucleic Acids Fodor et al. 6395491 Method of Information Storage and Recovery Fodor et al. 6406844 Very Large Scale Immobilized Polymer Synthesis Fodor et al. 6410229 Expression Monitoring by Hybridization to High Density Nucleic Acid Arrays Lockhart et al. 6416952 Photolithographic and other means for manufacturing arrays Pirrung et al. 6436647 Method for Detecting Chemical Interactions Between Naturally Occurring Biological Analyte Molecules that are Non-Identical Binding Partners Quate et al. 6440667 Analysis of Target Molecules Using an Encoding System Fodor et al. 6458530 Selecting Tag Nucleic Acids Morris et al. 6482591 Confirmationally Restricted Peptide Probe Libraries Lockhart et al. 6489114 Process for Labeling of a Ribonucleic Acid and Labeled RNA Fragments that are obtained thereby Laayoun et al. 6489146 End Complementary Polymer Reaction Stemmer et al. 6491871 System for Determining Ligand Binding Affinity Fodor et al. 6495320 Even Length Proportional Amplification of Nucleic Acids Lockhart et al. 6509160 Capturing Sequences Adjacent To Type IIS Restriction Sites for Genomic Library Mapping Sapolsky et al. 6524800 Exploiting Genomics in the Search for New Drugs Lockhart et al. 6544739 Method for Marking Samples Fodor et al. 6551784 Method of Comparing Nucleic Acid Sequences Fodor et al. 6573044 Methods of using chemical libraries to search for new kinase inhibitors Gray et al. 6576424 Arrays and Methods of Detecting Nucleic Acids Fodor et al. 6613516 Preparation of Nucleic Acid Samples Gingeras et al. 6632605 Hybridization Assays on Oligonucleotide Arrays Cronin et al. 6699659 Monomer Identification in Sample Mixtures of Polymers Webster et al 6733969 Expression Monitoring for Gene Function Identification Mack 6746844 Determining Signal Transduction Pathways Oliner et al 6803679 Methods and Compositions for Detecting Signals in Binding Assays using MicroArray Particles Lyon et al 6811981 Release of Intracellular Material Martin et al 6830890 Nucleic Acid Probe Libraries Lockhart et al 6841348 Methods of Identifying and Using Maintenance Genes Warrington 6852490 Method of Using an Array of Pooled Probes in Genetic Analysis Gentalen et al 6913882 Methods of Screening for B Cell Activity Modulators Glynne et al 6924094 Chip-Based Species Identification and Phenotypic Characterization of Microorganisms Gingeras et al 7108969 Methods for Detecting and Diagnosing Oral Cancer Warrington et al 7135285 Identification of Molecular Sequence Signatures and Methods Involving the Same Lockhart, et al 7144699 Iterative Resequencing Chee 7217521 Splicing Factor Target Identification Qian GENOTYPING USPN Title Inventor 5547839 Sequencing of surface immobilized polymers utilizing microflourescence detection Dower 5858659 Polymorphism detection Sapolsky 5925525 Method of Identifying nucleotide differences Fodor 5968740 Method of Identifying a Base in a Nucleic Acid Fodor 6197506 A Method of Detecting Nucleic Acids Fodor 6268141 Probe kit for identifying a base in a nucleic acid Matson et al. 6268152 Probe Kit for Identifying a Base in a Nucleic Acid Fodor 6284460 Probe Array Library and Method of Identifying a Base in a Nucleic Acid Fodor 6287778 Allele Detection using Primer Extension with Sequence Coded Identity Tags Huang 6300063 Polymorphism Detection Lipshutz 6333179 Methods and Compositions for Multiplex Amplification of Nucleic Acids Matsuzaki 6361947 Complexity Management and Analysis of Genomic Data Dong et al. 6391592 Blocker Aided Target Amplification of Nucleic Acids Su 6468744 Analysis of Genetic Polymorphisms and Gene Copy Number Chee et al. 6525185 Polymorphisms Associated with Hypertension Fan et al. 6632611 Method of Target Enrichment and Amplification Su et al. 6638719 Genotyping Biallelic Markers Gunderson et al. 6673579 Methods and Compositions for Multiplex Amplification of Nucleic Acids Matsuzaki et al. 6709816 Identification of Alleles Huang et al. 6852488 Identifying a Base in a Nucleic Acid Fodor et al 6872529 Complexity Management of Genomic Data Su 6953663 Polymorphism Detection Lipshutz et al 6958225 Complexity Management of Genomic Data Dong 7097976 Methods of Analysis of Allelic Imbalance Kennedy 7108976 Complexity Management of Genomic DNA by Locus Specific Amplification   7202039 Complexity Management of Genomic DNA Su 7208295 Multiple Oligonucleotide Addition and Target Amplification Faham, et al 7214490 Method of Target Enrichment and Amplification Su, et al EXPRESSION AND PROFILING USPN Title Inventor 5800992 Method of detecting nucleic acids Fodor 6013449 Probe-based analysis of heterozygous mutations using two-color labeling Hacia 6020135 p53-regulated genes Levine 6033860 Adult and fetal expression profiles in organs Lockhart 6040138 Expression monitoring by hybridization to high density oligonucleotide arrays Lockhart 6171798 p53 Regulated Genes Levine 6177248 Downstream Genes of Tumor Suppressor WT1 Oliner 6344316 Nucleic Acid Analysis Techniques Lockhart et al. 6391550 Identification of Sequence Signatures and Methods Involving Same Lockhart et al. 6548257 Methods of Identifying Nucleic Acid Probes to Quantify the Expression of a Target Nucleic Acid Lockhart et al. 6576424 Arrays and Methods for Detecting Nucleic Acids Fodor et al. 6670122 Method of Detecting Transcription Templates Rosenow et al 6794138 Methods of Small Sample Amplification Cao et al 6927032 Expression Monitoring by Hybridization to High Density Oligonucleotide Arrays Lockhart et al 6936416 Expression Monitoring for Human Cytomegalovirus (HCMV) Infection Gingeras et al 7089121 Methods for Monitoring the Expression of Alternatively Spliced Genes Wang ELECTROCHEMICAL ANALYSIS USPN Title Inventor 5527670 Electrochemical Denaturation of Double-Stranded Nucleic Acid Stanley 5607832 Use of multivalent inorganic actions in the electrochemical treatment of nucletic acid containing solutions Stanley 5814450 Sequencing of surface immobilized polymers utilizing microflourescence detection Stanley 5824477 Electrochemical Denaturation of Double-Stranded Nucleic Acid Stanley 6033850 Electrochemical Denaturation of Double-Stranded Nucleic Acid Purvis 6197508 Electrochemical Denaturation of Double-Stranded Nucleic Acid Stanley 6291185 Electrochemical Denaturation of Double-Stranded Nucleic Acids Purvis 6333157 Disassociation of Interacting Molecules Miller-Jones 6365400 Electrochemical Denaturation of Double-Stranded Nucleic Acids Stanley 6395489 Electrochemical Denaturation of Double-Stranded Nucleic Acids Stanley 6613527 Electrochemical Denaturation of Double Stranded Nucleic Acids Stanley 6794130 Nucleic Acid Pick-Up Pollard-Knight et al