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The Genome Generation | Let's make medicine personal

Advances in genomics and genetics have influenced the way we study disease at a molecular level and hold the promise to revolutionize the way medicine is practiced. The Genome Generation blog is the start of a conversation with you on how genomics can shape the future: from functional biology to translational medicine, from basic biology to diagnostic tools, from the bench to bedside. We want to find out your views; what is your story in the Genome Generation…

Validomics: How do we ensure biologically relevant data?

Posted on: May 14, 2012

In my previous post, I talked about the wealth of information being produced by high-throughput (HT) genomics methods and how post-genomic research is helping to paint a new picture of living processes. It was only very briefly that I touched upon and stressed the importance of data validation, particularly using additional experiments and orthogonal methods to validate results from the HT approaches. I could not have predicted what was about to appear! Read more >

Genomics, transcriptomics, proteomics – is it time for validomics?

Posted on: April 19, 2012

Today we celebrate DNA day, which commemorates the publication of the structure of DNA in 1953¹. On this very day in 2003, the Human Genome Project (HGP) was completed, providing us with a reference sequence of the human genome². The draft sequence had been provided two years earlier, in 2001³^,⁴. Since the completion of the HGP, tremendous progress has been made in the field of genomics, but there is criticism that the anticipated benefits in improved human health have yet to be realized. Some have claimed that that the likely benefits of the HGP were initially exaggerated to obtain funding for the project...Read more >

The Genome Generation

Posted on: March 9, 2012

Traditionally, a visit to the physician started with a discussion–ranging from the description of symptoms, to your medical history and family profile–and continued with a review of classical blood chemistry results, a physical examination and sometimes more advanced diagnostic tests such as biopsies and/or imaging...Read more >