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Genome-Wide Human SNP Array 6.0
Genome-Wide Human SNP Array 6.0
The SNP Array 6.0 demonstrates industry-leading performance and represents more genetic variation on a single array than any other product.
Pure Power and Performance
The new Affymetrix Genome-Wide Human SNP Array 6.0 features 1.8 million genetic markers, including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation. The SNP Array 6.0 is the only platform with analysis tools to truly bridge copy number and association, including a new, high-resolution reference map and a copy number polymorphism (CNP) calling algorithm developed by the Broad Institute. The SNP Array 6.0 demonstrates industry-leading performance and represents more genetic variation on a single array than any other product, providing maximum panel power and the highest physical coverage of the genome.
The high price-performance value of the SNP Array 6.0 enables researchers to design association studies with larger sample sizes in the initial scan and replication phases, thereby significantly increasing the overall genetic power of their studies.
New! Affymetrix Cytogenetics Research Solution
Affymetrix Copy Number Solution on SNP 6.0
Copy Number and LOH analysis tools in Genotyping Console
More than 906,600 SNPs:
- Unbiased selection of 482,000 SNPs; historical SNPs from the SNP Array 5.0
- Selection of additional 424,000 SNPs
- Tag SNPs
- SNPs from chromosomes X and Y
- Mitochondrial SNPs
- New SNPs added to the dbSNP database
- SNPs in recombination hotspots
More than 946,000 copy number probes:
- 202,000 probes targeting 5,677 CNV regions from the Toronto Database of Genomic Variants
- 744,000 probes, evenly spaced along the genome
- Detected 10 times more copy number changes than other SNP/CN platforms
- Three times more coverage of CNPs; only platform with non-polymorphic probes
- GTC 3.0 leverages new, high-resolution reference map and CNP calling algorithm developed by the Broad Institute
More Information:
New Software Tools for Copy Number and LOH Analysis
For research use only. Not for use in diagnostic procedures.
Application Notes
Copy-neutral Loss of Heterozygosity in Cancer (pdf, 1.07 MB)
A New Paradigm for Two-stage Association Studies (pdf, 144 KB)
Data Sheets
Genome-Wide Human SNP Array 6.0 (pdf, 846 KB)
Automated Genotyping Using the SNP Array 6.0 (pdf, 259 KB)
Library Files
Genome-Wide Human SNP Array 6.0 (zip, 246 MB)
Manuals
Cytogenetics Copy Number Assay User Guide (pdf, 2.6 MB)
Genome-Wide Human SNP Nsp/Sty 6.0 User Guide (pdf, 2.97 MB)
Affymetrix Human SNP Assay 6.0 User Guide for Automated Target Preparation (pdf, 2.62 MB)
Probe Set Data in MAGE-ML Format
Package Inserts
Genome-Wide Human SNP Array 6.0 (pdf, 102 KB)
Genome-Wide Human SNP Nsp/Sty Assay Kit 5.0/6.0 (pdf, 76 KB)
Protocol, Long
Genome-Wide Human SNP Array 6.0
Publications
Quick Reference Cards
SNP 6.0 Protocol for 48 Samples (pdf, 458 KB)
SNP 6.0 Protocol for 96 Samples (pdf, 512 KB)
Affymetrix Human SNP Assay 6.0 Automated Target Preparation (pdf, 496 KB)
Safety Data Sheets
Genome-Wide SNP 5.0/6.0 Assay Kits, without Reference DNA (zip, 292 KB)
Genome-Wide Human SNP 5.0/6.0 Assay Kits, with Reference DNA (zip, 333 KB)
Sample Data
Genome-Wide Human SNP Array 6.0 Sample Data Set
Technical Notes
Associating Copy Number and SNP Variation with Human Disease (pdf, 1.63 MB)
Use of Saliva gDNA for SNP Genotyping (pdf, 556 KB)
Linking Whole-genome Amplification to SNP Genotyping (pdf, 346 KB)
White Papers
Genotyping Console Quality Control Assessment (pdf, 1.07 MB)
Other
ReadMe, Genome-Wide Human SNP Array 6.0 Sample Data Set
Literature and Resource Guide for the Genome-Wide SNP Array 6.0 (pdf, 71 KB)
NetAffx Alignment Files
GenomeWideSNP_6 BED File (26 MB 11/28/07)
NetAffx Annotation Files
GenomeWideSNP_6 Meta Probeset File (825 KB 05/25/07)
GenomeWideSNP_6 CN Annotations, CSV format, Release 30 (67 MB 11/15/09)
GenomeWideSNP_6 Annotations, CSV format, Release 30 (297 MB 11/15/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 30 (495 MB 11/15/09)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference, Release 30 (173 MB 11/19/09)
Sequence Files
GenomeWideSNP_6 Probe Sequences, tabular format (51 MB 05/25/07)
GenomeWideSNP_6 CN Probe Sequences, tabular format (33 MB 05/25/07)
GenomeWideSNP_6 Flanking Sequences, FASTA format (13 MB 05/25/07)
Archived NetAffx Annotation Files
GenomeWideSNP_6 Annotations, SQLite Format, Release 29 (438 MB 10/13/09)
GenomeWideSNP_6 CN Annotations, CSV format, Release 22 (26 MB 05/25/07)
GenomeWideSNP_6 Annotations, CSV format, Release 22 (306 MB 05/25/07)
GenomeWideSNP_6 CN Annotations, CSV format, Release 23 (51 MB 07/18/07)
GenomeWideSNP_6 Annotations, CSV format, Release 23 (305 MB 07/18/07)
GenomeWideSNP_6 Annotations, CSV format, Release 24 (273 MB 11/28/07)
GenomeWideSNP_6 CN Annotations, CSV format, Release 24 (52 MB 11/28/07)
GenomeWideSNP_6 CN Annotations, CSV format, Release 25 (56 MB 04/29/08)
GenomeWideSNP_6 Annotations, CSV format, Release 25 (316 MB 04/29/08)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (157 MB 06/02/08)
GenomeWideSNP_6 CN Annotations, CSV format, Release 26 (56 MB 07/09/08)
GenomeWideSNP_6 Annotations, CSV format, Release 26 (322 MB 07/09/08)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (157 MB 07/14/08)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (157 MB 10/13/08)
GenomeWideSNP_6 Annotations, CSV format, Release 26 (316 MB 10/03/08)
GenomeWideSNP_6 CN Annotations, CSV format, Release 27 (60 MB 12/01/08)
GenomeWideSNP_6 Annotations, CSV format, Release 27 (294 MB 03/25/09)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (157 MB 12/04/08)
GenomeWideSNP_6 CN Annotations, CSV format, Release 28 (60 MB 03/06/09)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (157 MB 03/17/09)
GenomeWideSNP_6 CN Annotations, CSV format, Release 26 (60 MB 03/19/09)
GenomeWideSNP_6 Annotations, CSV format, Release 28 (295 MB 03/16/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 26.1 (511 MB 10/13/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 27 (488 MB 10/13/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 28 (490 MB 10/13/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 25 (484 MB 10/13/09)
GenomeWideSNP_6 Annotations, SQLite Format, Release 24 (425 MB 10/13/09)
GenomeWideSNP_6 CN Annotations, CSV format, Release 29 (56 MB 09/18/09)
GenomeWideSNP_6 Annotations, CSV format, Release 29 (259 MB 09/18/09)
GenomeWideSNP_6 Copy Number Analysis HapMap Reference (154 MB 07/23/09)
Required Products
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