GeneChip Human Mapping 500K Array Set
The GeneChip® Mapping 500K Array Set enables highly powered whole-genome association studies.
The GeneChip® Human Mapping 500K Array Set provides consistently high coverage across different populations. It is comprised of two arrays, each capable of genotyping on average 250,000 SNPs (approximately 262,000 for Nsp arrays and 238,000 for Sty arrays). The Mapping 500K Array Set uses the same proven assay as the GeneChip® Mapping 10K Array and Mapping 100K Set that has been validated in over 120 published studies in less than three years.
May 2006 — A series of updates to the Mapping 500K system is launched, including:
- BRLMM, a new genotype calling algorithm. New and existing Mapping 500K Array Set data can now be re-analyzed to increase both call rates and accuracy.
- 96-well plate protocol, enabling faster and more consistent ramp-up to high throughput sample processing.
Benefits of the Mapping 500K Array Set
- Consistently high coverage across different populations
View Genome coverage of 500K SNPs (Figure 1)
- Reference standard for whole-genome association
Community creating database of >10,000 control samples
Gain consortium to release Mapping 500K Array Set data to the public domain
- Proven approach for discovery
See list of nearly 250 publications (pdf, 159 KB) on mapping assay
Download updated Assay Manual (pdf, 3.4 MB) which includes protocol for 96-well plate processing
- Broad compatibility with DNA sample collections
250 ng of raw genomic DNA
Compatible with whole-genome amplified DNA
- Highest throughput on the market
100 samples/week/instrument
Learn more about GeneChip® Scanner 3000, with AutoLoader
- Innovative solutions available for data analysis and management
Learn about BRLMM, a genotype calling algorithm
Learn about GeneChip-compatible third-party software for downstream analysis
Find out more about Clontech's Titanium DNA Amplification Kit for use with the Whole Genome Sampling Assay.
For research use only. Not for use in diagnostic procedures.

Application Notes
Microarrays in Cancer Research (pdf, 423 KB)
Data Sheets
GeneChip Human Mapping 500K Array Set (pdf, 192 KB)
Library Files
Mapping 250K Sty Array (zip, 42 MB)
Mapping 250K Nsp Array (zip, 43 MB)
Manuals
Probe Set Data in MAGE-ML Format
Mapping 500K Assay Manual (pdf, 3.4 MB)
Package Inserts
Mapping 500K Array Set (pdf, 97 KB)
Mapping 500K Assay Kit (pdf, 83 KB)
Protocol, Long
Quick Reference Cards
GeneChip Mapping 500K Array Set (zip, .99 MB)
Safety Data Sheets
Mapping 500K Array Set, Nsp Array (zip, 303 KB)
Mapping 500K Array Set, Sty Array (zip, 345 KB)
Sample Data
Mapping 500K HapMap Genotype Data Set
White Papers
BRLMM Algorithm for Affymetrix Mapping Arrays (pdf, 278 KB)
Other
Mapping 500K Nsp Reference DNA Concordance (zip, 3.5 MB)
Mapping 500K Sty Reference DNA Concordance (zip, 3.5 MB)
Mapping 500K Nsp Reference Genotype Calls (zip, 671 KB)
Mapping 500K Sty Reference Genotype Calls (zip, 612 KB)
NetAffx Alignment Files
Mapping250K_Nsp BED File (4 MB 11/28/07)
Mapping250K_Sty BED File (4 MB 11/28/07)
NetAffx Annotation Files
Mapping250K_Nsp Annotations, GTYPE Format, Release 21 (53 MB 01/02/07)
Mapping250K_Sty Annotations, GTYPE Format, Release 21 (49 MB 01/02/07)
Mapping250K_Nsp Annotations, CSV format, Release 30 (85 MB 11/15/09)
Mapping250K_Sty Annotations, CSV format, Release 30 (77 MB 11/15/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 30 (208 MB 11/15/09)
Mapping250K_Sty Annotations, SQLite Format, Release 30 (208 MB 11/15/09)
Sequence Files
Mapping250K_Nsp Flanking Sequences, FASTA (4 MB 08/20/08)
Mapping250K_Nsp Probe Sequences, Tabular (36 MB 08/20/08)
Mapping250K_Sty Flanking Sequences, FASTA (3 MB 08/20/08)
Mapping250K_Sty Probe Sequences, Tabular (36 MB 08/20/08)
Archived NetAffx Annotation Files
Mapping250K_Nsp Annotations, CSV, Release 20 (84 MB 06/15/06)
Mapping250K_Nsp Annotations, GTYPE, Release 20 (56 MB 03/09/06)
Mapping250K_Sty Annotations, CSV, Release 20 (76 MB 06/15/06)
Mapping250K_Sty Annotations, GTYPE, Release 20 (51 MB 03/09/06)
Mapping250K_Nsp Annotations, SQLite Format, Release 29 (185 MB 10/13/09)
Mapping250K_Nsp Annotations, CSV format, Release 21 (81 MB 01/29/07)
Mapping250K_Sty Annotations, CSV format, Release 21 (75 MB 01/29/07)
Mapping250K_Nsp Annotations, CSV format, Release 22 (84 MB 03/09/07)
Mapping250K_Sty Annotations, CSV format, Release 22 (77 MB 03/09/07)
Mapping250K_Nsp Annotations, CSV format, Release 23 (87 MB 07/12/07)
Mapping250K_Sty Annotations, CSV format, Release 23 (80 MB 07/12/07)
Mapping250K_Nsp Annotations, CSV format, Release 24 (78 MB 11/28/07)
Mapping250K_Sty Annotations, CSV format, Release 24 (71 MB 11/28/07)
Mapping250K_Nsp Annotations, CSV format, Release 25 (90 MB 04/07/08)
Mapping250K_Sty Annotations, CSV format, Release 25 (84 MB 04/07/08)
Mapping250K_Nsp Annotations, CSV format, Release 26 (92 MB 07/09/08)
Mapping250K_Sty Annotations, CSV format, Release 26 (85 MB 07/09/08)
Mapping250K_Nsp Annotations, CSV format, Release 27 (83 MB 11/25/08)
Mapping250K_Sty Annotations, CSV format, Release 27 (77 MB 11/25/08)
Mapping250K_Nsp Annotations, CSV format, Release 28 (84 MB 03/06/09)
Mapping250K_Sty Annotations, CSV format, Release 28 (78 MB 03/06/09)
Mapping250K_Sty Annotations, SQLite Format, Release 29 (185 MB 10/13/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 24 (188 MB 10/13/09)
Mapping250K_Sty Annotations, SQLite Format, Release 24 (188 MB 10/13/09)
Mapping250K_Sty Annotations, SQLite Format, Release 28 (211 MB 10/13/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 28 (211 MB 10/13/09)
Mapping250K_Sty Annotations, SQLite Format, Release 27 (210 MB 10/13/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 27 (210 MB 10/13/09)
Mapping250K_Sty Annotations, SQLite Format, Release 26 (223 MB 10/13/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 26 (223 MB 10/13/09)
Mapping250K_Sty Annotations, SQLite Format, Release 25 (219 MB 10/13/09)
Mapping250K_Nsp Annotations, SQLite Format, Release 25 (219 MB 10/13/09)
Mapping250K_Nsp Annotations, CSV format, Release 29 (74 MB 07/08/09)
Mapping250K_Sty Annotations, CSV format, Release 29 (68 MB 07/08/09)

Required Products
Related Products
| Genome-Wide Human SNP Array 6.0 |
| Genome-Wide Human SNP Array 5.0 |




